… suffice, hence our attempt at a targeted functional approach. … New techniques of surfactant
administration in combination … reported in the use of surfactant in ALI/ARDS, we agree with …

… on this, to create a consensus opinion about future research steps in this field. The … on
surfactant biology during ARDS and (2) randomized controlled trials comparing surfactant therapy …

… in COVID-19 ARDS, providing insights for future research. Methods: … surfactant therapy in
COVID-19 ARDS in our case series. … to patients with ALI/ARDS. One trial showed that synthetic …

… surfactants is to diminish surface tension in the alveoli at the air–liquid interface and inhibit
its collapse at … current results for SP-D in ALI/ARDS from preclinical and clinical studies. Our …

… during a few days, which is often manifested as an acute lung injury/acute respiratory distress
syndrome (ALI/ARDS), … In the future, more basic experiments or clinical studies should be …

… and highlights areas of future perspectives in therapeutics. … The cuboidal type II AECs
secrete a surfactant that is believed … a causal factor for development of ALI/ARDS [51]. However, …

… , and during this specific period exogenous surfactant treatment may be considered (11). …
Therefore, we decided to use budesonide combined with surfactant treatment to (i) minimize …

… In this review, ALI/ARDS gene therapy is discussed mainly in … Type II epithelial cells produce
surfactant proteins, which … be reported for the treatment of ALI/ARDS in the near future. …

… of new approaches optimizing surfactant therapy for the treatment of … There are several
agents able to injure surfactant through … pattern of surfactant injury will be crucial in the future to …

… of the triggering events of ALI/ARDS and progressively worsened over … or ICU treatment.
The most common symptoms … The repair process is initiated during this phase, and surfactant …